Colorectal Cancer and Ovarian Cancer
| Code | School | Level | Credits | Semesters |
| ONCG2003 | Cancer and Stem Cells | 2 | 20 | Autumn UK |
- Code
- ONCG2003
- School
- Cancer and Stem Cells
- Level
- 2
- Credits
- 20
- Semesters
- Autumn UK
Summary
This module considers:
• DNA repair mechanisms and the role these play in genetic stability
• Cancer stem cells and tumourigenesis
• Colorectal cancer progression to invasion and metastasis
• Ovarian cancer and drug resistance mechanisms
Target Students
Students studying Cancer Sciences BSc U6UCANCS (B131) and Cancer Sciences MSci U7UCANCSY (B130) and other students with the required pre-requisites including students studying Natural Sciences.
Co-requisites
Modules you must take in the same academic year, or have taken in a previous year, to enrol in this module:
Classes
- One 1-hour workshop
- One 1-hour tutorial
- One 6-hour seminar
- One 5-hour practicum
- One 1-hour lecture each week for 10 weeks
10 lectures; Practical class (histopathology computer-based session - 5 hours); Group data analysis coursework session and student presentations (6 hours); Open office session (1 hour); Revision workshop (1 hour).
Assessment
- 20% Coursework 1: 1,000 word essay
- 10% Practical 1: Data analysis worksheet linked to practical component
- 70% Exam 1 (1-hour): MCQ Exam - 1 hour
Assessed by end of autumn semester
Educational Aims
To describe DNA repair mechanisms and outline their importance in tumourigenesis with reference to colorectal cancer and other cancers. To understand the concept of the stem cell niche and the cancer stem cell. To understand cancer progression as exemplified by colorectal cancer. To understand the acquisition of drug resistance as exemplified by ovarian cancer.Learning Outcomes
1. Intellectual skills -
Students should be able to demonstrate a good understanding of:
• DNA repair mechanisms and their importance in tumourigenesis
• Stem cells and the importance of cancer stem cells
• Cancer progression in colorectal cancer
• Ovarian cancer
• Drug resistance mechanisms
2. Professional / practical skills -
Students should be able to demonstrate a good understanding of the use of histopathology in cancer diagnosis.
3. Transferable / key skills
Students should be able:
• Communicate complex written information to a non-specialist audience
• Communicate complex written information in the form of an extended essay
• Demonstrate self-management in the completion of course work
• Demonstrate problem solving skills and critical thinking as applied to relevant data
• Show basic levels of information technology literacy
Conveners
- Prof Mohammed Ilyas