Cancer Cell Genetics
| Code | School | Level | Credits | Semesters |
| ONCG2002 | Cancer and Stem Cells | 2 | 20 | Autumn UK |
- Code
- ONCG2002
- School
- Cancer and Stem Cells
- Level
- 2
- Credits
- 20
- Semesters
- Autumn UK
Summary
This module considers:
• Genetic polymorphisms and genome-wide association studies
• Chemical, viral, and radiation induced DNA damage and tumourigenesis
• Cancer cell genomics and the 100,000 genome project
• Cancer cell transcriptomics and epigenomics
• Precision medicine in cancer treatment
Target Students
Students studying Cancer Sciences BSc U6UCANCS (B131) and Cancer Sciences MSci U7UCANCSY (B130) and other students with the required pre-requisites including students studying Natural Sciences.
Co-requisites
Modules you must take in the same academic year, or have taken in a previous year, to enrol in this module:
Classes
- One 1-hour workshop
- One 5-hour workshop
- One 1-hour tutorial
- One 6-hour seminar
- One 5-hour practicum
- One 1-hour lecture each week for 13 weeks
13 lectures; Practical class (computer-based practical on cancer genomics - 5 hours); Group data analysis coursework session and student presentations (6 hours); Workshop based on chromatin immunoprecipitation and quantitative PCR - (5 hours); Open office session (1 hour); Revision workshop (1 hour).
Assessment
- 20% Coursework 1: 1000 word essay
- 10% Coursework 2: Practical 1 -Data analysis worksheet linked to practical component
- 70% Exam 1 (1-hour): Exam 1 MCQ 1 hour
Assessed by end of autumn semester
Educational Aims
To understand the causes of genetic changes in cancer cells and the evolution of the cancer cell genome during cancer progression. To understand the tools that are used to study the cancer cell genome, epigenome, and transcriptome and how these tools can guide precision medicine.Learning Outcomes
Students should be able to demonstrate a good understanding of:
The origins of genetic changes in cancer cells
Cancer cell genomics and epigenomics
Transcriptomics as applied to cancer biology
Cancer cell evolution and its impact on cancer metastasis and treatment
Precision medicine in cancer treatment
Students should be able to use appropriate online tools to investigate the cancer cell genome.
Students should be able to:
Communicate complex written information to a non-specialist audience
Communicate complex written information in the form of an extended essay
Demonstrate self-management in the completion of course work
Demonstrate problem solving skills and critical thinking as applied to relevant data
Show advanced levels of information technology literacy as applied to cancer cell genomics
• Cancer cell genomics and epigenomics
• Transcriptomics as applied to cancer biology
• Cancer cell evolution and its impact on cancer metastasis and treatment
• Precision medicine in cancer treatment
2. Professional / practical skills -
Students should be able to use appropriate online tools to investigate the cancer cell genome.
3. Transferable / key skills
Students should be able:
• Communicate complex written information to a non-specialist audience
• Communicate complex written information in the form of an extended essay
• Demonstrate self-management in the completion of course work
• Demonstrate problem solving skills and critical thinking as applied to relevant data
• Show advanced levels of information technology literacy as applied to cancer cell genomics