Cancer and clinical genetics
| Code | School | Level | Credits | Semesters |
| LIFE2110 | Biomedical Sciences | 2 | 10 | Autumn Malaysia |
- Code
- LIFE2110
- School
- Biomedical Sciences
- Level
- 2
- Credits
- 10
- Semesters
- Autumn Malaysia
Summary
This module covers the molecular mechanisms for human diseases with a genetic component. The lectures will cover clinical features and the genetic basis of selected diseases. This also include discussion of mutation detection and genetic assessment methods to provide experience in interpreting genetic modes of inheritance and tests of inherited disorders. Another major focus of this module is the most recent developments in cancer genetics. It will include consideration of the biological mechanisms underlying specific cancer types, discussion of how recent genomic studies have led to the identification of genes that play important roles in cancer formation, and outline how molecular genetic techniques are facilitating rapid advances in this field. In addition, we will consider how these advances in the understanding of cancer are influencing the development of new treatments.
Target Students
Biomedical Sciences students
Classes
- One 3-hour workshop
- One 3-hour seminar
- Two 2-hour lectures each week for 11 weeks
Assessment
- 30% Seminar Presentation: Students will be presenting in groups after preparation on a given topic during facilitated seminar
- 70% Exam (1-hour-30-minute): 1 hour 30 mins Rogo exam
Assessed by end of autumn semester
Educational Aims
To understand the genetic basis of various genetic disorders and cancers. To understand the assessments that are used to study the cell genome, epigenome, and transcriptome and how these tools can guide screening, diagnosis, monitoring and treatment of genetic diseases.Learning Outcomes
By the end of this course, students should be able to:
1) Describe the principles of Mendelian inheritance and the genetic basis and clinical features of selected Mendelian and non-Mendelian disorders and cancer subtypes
2) Describe mutation detection and how genetic assessments can aid in the screening, diagnosis, monitoring and treatment of genetic diseases
3) Explain the multi-step development of cancer and the role of key regulators in these steps
4) Evaluate the experimental evidence used to elucidate disease pathways and inform treatment strategies
Conveners
- Dr Wan Yong Ho