Intermediate Organic Spectroscopy and Synthesis
| Code | School | Level | Credits | Semesters |
| CHEM2002 | Chemistry | 2 | 10 | Autumn UK |
- Code
- CHEM2002
- School
- Chemistry
- Level
- 2
- Credits
- 10
- Semesters
- Autumn UK
Summary
The module provides both a theoretical description of modern spectroscopic techniques (NMR, IR, and mass spectrometry) for structural analysis of organic and biological molecules and practical applications of these techniques in problem solving. Aspects of the synthesis of bio-organic molecules are covered, including conformational analysis and stereocontrol in bio-organic reactions.
Target Students
Only available for BSc/MSci Chemistry and Molecular Physics OR Natural Sciences OR BSc/MSci Biochemistry AND Only available for Level 2 students.CHEM2002 cannot be taken if student is taking/has taken CHEM2010.
Classes
- One 1-hour workshop each week for 2 weeks
- Two 1-hour tutorials each week for 2 weeks
- Two 1-hour lectures each week for 10 weeks
Assessment
- 100% Exam 1 (2-hour): If a further re-assessment is allowed under Undergraduate Course Regulation 19, the form of the re-assessment for this module will be 100% coursework.
Assessed by end of autumn semester
Educational Aims
Develop an understanding of modern spectroscopic techniques (NMR, IR, UV and mass spectrometry) for the characterisation of organic and biological molecules to the extent that students have an intuitive approach to problem solving and structural analysis. Aspects of the synthesis of molecular fragments, including aromaticity, electrophilic substitutions, enol/enolate chemistry and the preparation/reactions of heterocycles are developed.Learning Outcomes
Knowledge and Understanding: Students should have an understanding of:
1. The theory of NMR including the origin of 1H and 13C chemical shifts and J-couplings.
2. The basics of IR spectroscopy and modes of vibration;
3. Mass spectrometry as complementary methods in structural analysis.
4. Conformational analysis and stereocontrol in bio-organic reactions.
Intellectual Skills: Be able to:
1. Carry out structural analysis in a problem-solving context.
2. Identify characteristic 1H NMR, 13C NMR, and IR signals related to chemical structure.
3. Use stereochemical issues to predict structure and chemical reactivity.
Transferable/Key Skills: Problem-solving and written communication skills.